Effects of Acute Dopamine Precusor Depletion on Immediate Reward Selection Bias and Working Memory Depend on Catechol-O-methyltransferase Genotype

@article{Kelm2013EffectsOA,
  title={Effects of Acute Dopamine Precusor Depletion on Immediate Reward Selection Bias and Working Memory Depend on Catechol-O-methyltransferase Genotype},
  author={Mary Katherine Kelm and Charlotte A. Boettiger},
  journal={Journal of Cognitive Neuroscience},
  year={2013},
  volume={25},
  pages={2061-2071}
}
Little agreement exists as to acute dopamine (DA) manipulation effects on intertemporal choice in humans. We previously found that catechol-O-methyltransferase (COMT) Val158Met genotype predicts individual differences in immediate reward selection bias among adults. Moreover, we and others have shown that the relationship between COMT genotype and immediate… CONTINUE READING