Effects of APOE and CHRNA4 genotypes on retinal nerve fibre layer thickness at the optic disc and on risk for developing exfoliation syndrome.

@article{Ritland2007EffectsOA,
  title={Effects of APOE and CHRNA4 genotypes on retinal nerve fibre layer thickness at the optic disc and on risk for developing exfoliation syndrome.},
  author={Jon St{\aa}le Ritland and Tor Paaske Utheim and Oygunn Aass Utheim and Thomas Espeseth and Stian Lydersen and Svein Ove Semb and Helge Rootwelt and Tor B Els{\aa}s},
  journal={Acta ophthalmologica Scandinavica},
  year={2007},
  volume={85 3},
  pages={
          257-61
        }
}
PURPOSE To investigate whether CHRNA4 and APOE genotypes influence retinal nerve fibre layer (RNFL) thickness at the optic disc, intraocular pressure (IOP) and the development of exfoliation syndrome (XFS). METHODS A sample of 88 healthy adults (aged 50-75 years) genotyped for polymorphisms of APOE and CHRNA4 underwent an eye examination including slit-lamp examination and fundus photography, as well as measurements of visual acuity, refraction, IOP and RNFL thickness at the optic disc by… CONTINUE READING