Effects of ACNU and radiotherapy on malignant glioma.

@article{Takakura1986EffectsOA,
  title={Effects of ACNU and radiotherapy on malignant glioma.},
  author={Kintomo Takakura and Hiroyuki Abe and Ryuichi Tanaka and Koichi Kitamura and Takaya Miwa and Kazuo Takeuchi and Satoru Yamamoto and Naoki Kageyama and Hajime Handa and Hiroshi Mogami},
  journal={Journal of neurosurgery},
  year={1986},
  volume={64 1},
  pages={
          53-7
        }
}
A randomized clinical study of irradiation and irradiation combined with ACNU in the treatment of malignant gliomas was performed in order to determine if there was an enhancing therapeutic effect of ACNU given in addition to radiotherapy. An effect was defined as a reduction in tumor size, changes in neurological signs and performance status within 1 month after the completion of radiotherapy, or statistically improved survival times. Seventy-seven patients from 14 neurosurgical clinics were… CONTINUE READING
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Treatment of Glioma

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