Effects of 5 alpha reductase inhibitors on androgen-dependent human prostatic carcinoma cells


To investigate the effects of MK906, a selective 5 alpha reductase (5αR) type 2 (5αR2) inhibitor, and of MK386, a specific 5αR1 inhibitor, on the cellular proliferation of androgen-dependent human prostatic cancer (PCa) cells in cultures of cells derived from bioptic and surgical tissues. In this study we tested the effects of MK906 and MK386 in 30 cultures… (More)
DOI: 10.1007/s00432-004-0632-1


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