Effects of 5-HT agonists, selective for different receptor subtypes, on oxytocin, CCK, gastrin and somatostatin plasma levels in the rat

@article{UvnsMoberg1996EffectsO5,
  title={Effects of 5-HT agonists, selective for different receptor subtypes, on oxytocin, CCK, gastrin and somatostatin plasma levels in the rat},
  author={K. Uvn{\"a}s-Moberg and V. Hillegaart and P. Alster and S. Ahl{\'e}nius},
  journal={Neuropharmacology},
  year={1996},
  volume={35},
  pages={1635-1640}
}
  • K. Uvnäs-Moberg, V. Hillegaart, +1 author S. Ahlénius
  • Published 1996
  • Psychology, Medicine
  • Neuropharmacology
  • Adult male Sprague-Dawley rats were administered the 5-HT subtype selective receptor agonists 8-OH-DPAT (0.5-2.0 mg/kg), buspirone (2-8 mg/kg) (5-HT1A), TFMPP (0.125-2.0 mg/kg) (5-HT1B), DOI (0.125-2.0 mg/kg) (5-HT2A) and m-CPBG (1.25-20.0 mg/kg) (5-HT3), subcutaneously. Oxytocin, cholecystokinin (CCK), somatostatin and gastrin plasma levels were determined by standard RIA techniques 30 and 120 min after injection of the respective 5-HT receptor agonist. It was found that the 5-HT1A and the 5… CONTINUE READING
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