Effects of 5‐HT drugs in prefrontal cortex during memory formation and the ketamine amnesia‐model
@article{LiySalmeron2008EffectsO5, title={Effects of 5‐HT drugs in prefrontal cortex during memory formation and the ketamine amnesia‐model}, author={Gustavo Liy-Salmeron and A. Meneses}, journal={Hippocampus}, year={2008}, volume={18} }
This article describes a series of experiments investigating the effects of systemic or intraprefrontal administration of serotonergic agents on ketamine induced memory deficits in rats. First, rats were trained on an operant autoshaping task. Immediately after training, rats were injected with different doses of drug or saline. Following drug administration, rats were tested after 1.5 h for short‐term memory (STM) and 24 h for long‐term memory (LTM) of conditioned response. An increase or… CONTINUE READING
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