Effects of 24,25-dihydroxy-vitamin D3 on the hypercalcemic action of 1α-hydroxy-vitamin D3

@article{Bauman2004EffectsO2,
  title={Effects of 24,25-dihydroxy-vitamin D3 on the hypercalcemic action of 1α-hydroxy-vitamin D3},
  author={V. K. Bauman and M. D. Valinietse and R. {\'E}. Andrushaite and Dmitry Babarykin},
  journal={Pharmaceutical Chemistry Journal},
  year={2004},
  volume={22},
  pages={879-884}
}
An active metabolite of vitamin Ds -l~,25-dihydroxy-vitamin Ds [I,25(OH) 2D3], formed in the kidneys, performs the function of a steroid hormone in the animal organism, regulating the metabolism of Ca and P. The administration of 1,25(OH)=D3 to animals with rickets produces an intensification of the process of absorpti0n of Ca and P in the small intestine, a rapid restoration of their level in the blood, and an increase in the mineralization of bone tissue [16]. However, it has been noted in a… CONTINUE READING