Effects of 17beta-oestradiol on cerebral ischaemic damage and lipid peroxidation.

@article{Gordon2005EffectsO1,
  title={Effects of 17beta-oestradiol on cerebral ischaemic damage and lipid peroxidation.},
  author={Kirsty B Gordon and I Mhairi Macrae and Hilary V O Carswell},
  journal={Brain research},
  year={2005},
  volume={1036 1-2},
  pages={155-62}
}
INTRODUCTION Numerous studies demonstrate oestrogen's neuroprotective effect in stroke models, although the mechanisms are unclear. Since oestrogen is an antioxidant, we tested the hypothesis that oestrogen reduces stroke-induced damage by reducing free radical damage, particularly lipid peroxidation. METHODS Sprague-Dawley rats were ovariectomised and a 17beta-oestradiol (0.25 mg, 21 day release) or placebo pellet implanted subcutaneously. Two weeks later, permanent middle cerebral artery… CONTINUE READING
27 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 27 extracted citations

Similar Papers

Loading similar papers…