Effects of 12-month GH treatment on bone metabolism and bone mineral density in adults with adult-onset GH deficiency.

@article{Sartorio2001EffectsO1,
  title={Effects of 12-month GH treatment on bone metabolism and bone mineral density in adults with adult-onset GH deficiency.},
  author={Alessandro Sartorio and Sergio Ortolani and Elisabetta Galbiati and Giuseppe Conte and V. Vangeli and Maura Arosio and Silvia Porretti and Giovanni Faglia},
  journal={Journal of endocrinological investigation},
  year={2001},
  volume={24 4},
  pages={224-30}
}
Serum bone-Gla protein (BGP), bone alkaline phosphatase (B-AP), and C-terminal cross-linked telopeptide of type I collagen (ICTP) levels were evaluated in 18 adults with acquired GH deficiency (GHD, 14 males and 4 females, age range: 25-59 yr) before, at 3, 6, 9 and 12 months of rec-GH treatment (0.125 IU/kg/week for the first month, followed by 0.25 IU/kg/week for 11 months) and 6 months after the withdrawal of therapy. Total body bone mineral density (BMD, g/cm2) was measured with dual energy… CONTINUE READING