Effects of α2 and 2′-5′-oligoadenylate on tetrodotoxin-sensitive sodium transport in neuroblastoma cellsand 2′-5′-oligoadenylate on tetrodotoxin-sensitive sodium transport in neuroblastoma cells

We investigated the actions of human recombinant α2-interferon and a secondary messenger of its action, 2′-5′-oligoadenylate, on tetrodotoxin (TTX)-sensitive sodium transport using human (IMR-32) and murine (NIE-115) neuroblastoma cells. In biochemical experiments using22Na, human interferon was shown to increase entry of22Na into IMR-32 neuroblastoma cells… (More)