Effects of α-lipoic acid on neurovascular function in diabetic rats: interaction with essential fatty acids

Abstract

Elevated oxidative stress and impaired n-6 essential fatty acid metabolism contribute to defective nerve conduction velocity (NCV) and perfusion in diabetic rats, which may be corrected by free radical scavenger and γ-linolenic acid (GLA) treatments. α-Lipoic acid (LPA) has antioxidant actions and both LPA racemate (racLPA) and GLA treatments produced… (More)
DOI: 10.1007/s001250050921

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