Effects of α-lipoic acid on high-glucose induced transdifferentiation of human renal tubular epithelial cells

@inproceedings{Lan2013EffectsO,
  title={Effects of α-lipoic acid on high-glucose induced transdifferentiation of human renal tubular epithelial cells},
  author={Shi Lan},
  year={2013}
}
Objective To investigate the effects of α-lipoic acid on transdifferentiation of renal tubular epithelial cell induced by high-glucose.Methods Human renal tubular epithelial cells(HKC) were cultured in DMEM medium and divided into six groups: normal glucose group(5.5 mmol/L),mannitol group(5.5 mmol/L glucose plus 19.5 mmol/L mannitol),high glucose group(25 mmol/L),and α-lipoic acid groups(high glucose with 100 μmol/L,200 μmol/L and 400 μmol/L α-lipoic acid respectively).The morphology of HKC… CONTINUE READING

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