Effects and side effects associated with the non-nutritional use of tryptophan by humans.

@article{Fernstrom2012EffectsAS,
  title={Effects and side effects associated with the non-nutritional use of tryptophan by humans.},
  author={John D. Fernstrom},
  journal={The Journal of nutrition},
  year={2012},
  volume={142 12},
  pages={2236S-2244S}
}
The daily nutritional requirement for L-tryptophan (Trp) is modest (5 mg/kg). However, many adults choose to consume much more, up to 4-5 g/d (60-70 mg/kg), typically to improve mood or sleep. Ingesting L-Trp raises brain tryptophan levels and stimulates its conversion to serotonin in neurons, which is thought to mediate its actions. Are there side effects from Trp supplementation? Some consider drowsiness a side effect, but not those who use it to improve sleep. Though the literature is thin… CONTINUE READING
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