Effects and side‐effects of 2% progesterone cream on the skin of peri‐ and postmenopausal women: results from a double‐blind, vehicle‐controlled, randomized study

@article{Holzer2005EffectsAS,
  title={Effects and side‐effects of 2\% progesterone cream on the skin of peri‐ and postmenopausal women: results from a double‐blind, vehicle‐controlled, randomized study},
  author={G. Holzer and E. Riegler and H. H{\"o}nigsmann and S. Farokhnia and B. Schmidt},
  journal={British Journal of Dermatology},
  year={2005},
  volume={153}
}
Background  For many years topical progesterone has been prescribed by gynaecologists as an antiageing and skin‐firming treatment, without any clinical scientific evidence of its effects, tolerability and safety when applied to skin. 
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  • 2007
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TLDR
The pharmacokinetics of a progesterone cream following short and long term dermal administration are studied to determine the pharmacokinetic properties of the cream and to determine its application in the vaginal and laparoscopic setting. Expand
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The objective to examine the effect of topical oestradiol on skin collagen and elastin and to propose a new drug to treat eczema. Expand
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The data suggest that skin collagen is influenced by the sex hormone status arid declines after the menopause contributing to the increase in urinary hydroxyproline excretion that has been reported to occur this time. Expand
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