Effects and aftereffects of ibogaine on morphine self-administration in rats.

  title={Effects and aftereffects of ibogaine on morphine self-administration in rats.},
  author={S. D. Glick and K. Rossman and S. Steindorf and I. M. Maisonneuve and J. Carlson},
  journal={European journal of pharmacology},
  volume={195 3},
Ibogaine, a naturally occurring alkaloid, has been claimed to be effective in treating addition to opiate and stimulant drugs. [...] Key Result Ibogaine dose dependently (2.5-80 mg/kg) decreased morphine intake in the hour after ibogaine treatment (acute effect) and, to a lesser extent, a day later (aftereffect); while the acute effect could be attributed to abnormal motor behavior (whole body tremors), the aftereffect occurred at a time when ibogaine should have been entirely eliminated from the body and when…Expand
179 Citations
Ibogaine-like effects of noribogaine in rats
  • 65
  • PDF
Short communication Ibogaine-like effects of noribogaine in rats
  • Highly Influenced
Inhibitory effects of ibogaine on cocaine self-administration in rats.
  • 162
  • PDF
Long-Lasting Ibogaine Protection against NMDA-Induced Convulsions in Mice
  • 22
In Vivo Ibogaine Blockade and In Vitro PKC Action of Cocaine a
  • 12
Sex Differences in Ibogaine Antagonism of Morphine-induced Locomotor Activity and in Ibogaine Brain Levels and Metabolism
  • 47
  • PDF


Benzodiazepine receptors are involved in tabernanthine-induced tremor: in vitro and in vivo evidence.
  • 31
Chapter 6 – Long-term Intravenous Infusion
  • 222
The role of reward pathways in the development of drug dependence.
  • R. Wise
  • Biology, Medicine
  • Pharmacology & therapeutics
  • 1987
  • 420
A psychomotor stimulant theory of addiction.
  • 2,657
  • PDF
Cerebral pharmacokinetics of tremor-producing harmala and iboga alkaloids.
  • 97
Benzodinzepine receptors are involved in tabernanthine - induced tremor : in vitro and in viva evidence
  • European J . Pharmncot .
  • 1987
The rote of reward palhways in the development ot drug dependence
  • Pharmacol . Ther .
  • 1987