Effector stage CC chemokine receptor-1 selective antagonism reduces multiple sclerosis-like rat disease.

@article{Eltayeb2003EffectorSC,
  title={Effector stage CC chemokine receptor-1 selective antagonism reduces multiple sclerosis-like rat disease.},
  author={Sana Eltayeb and Dan Sunnemark and Anna-Lena Berg and Gunnar Nordvall and Asa Malmberg and Hans Lassmann and Erik Wallstr{\"o}m and Tomas Olsson and Anders Ericsson-Dahlstrand},
  journal={Journal of neuroimmunology},
  year={2003},
  volume={142 1-2},
  pages={75-85}
}
We have studied the role of the chemokine receptor CCR1 during the effector stage of myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis in DA rats. In situ hybridization histochemistry revealed local production of the CCR1 ligands CCL3 (MIP-1 alpha) and CCL5 (RANTES), as well as large numbers of CCR1 and CCR5 expressing… CONTINUE READING