Effector cytotoxic T lymphocyte numbers induced by vaccination should exceed levels in chronic infection for protection from HIV.

@article{Altes2001EffectorCT,
  title={Effector cytotoxic T lymphocyte numbers induced by vaccination should exceed levels in chronic infection for protection from HIV.},
  author={Hester Korthals Altes and David A. Price and Vincent A A Jansen},
  journal={Vaccine},
  year={2001},
  volume={20 1-2},
  pages={3-6}
}
Recent technological advances have revolutionised our capacity to induce cytotoxic T lymphocyte (CTL) responses with a variety of vaccine formulations and delivery systems. However, the conditions required for a CTL-inducing vaccine to provide protection from infection or disease are poorly understood, and the results of challenge experiments have not been… CONTINUE READING