Effector Caspases and Leukemia

@inproceedings{Lu2011EffectorCA,
  title={Effector Caspases and Leukemia},
  author={Ying Lu and Guo-Qiang Chen},
  booktitle={International journal of cell biology},
  year={2011}
}
Caspases, a family of aspartate-specific cysteine proteases, play a major role in apoptosis and a variety of physiological and pathological processes. Fourteen mammalian caspases have been identified and can be divided into two groups: inflammatory caspases and apoptotic caspases. Based on the structure and function, the apoptotic caspases are further grouped into initiator/apical caspases (caspase-2, -8, -9, and -10) and effector/executioner caspases (caspase-3, -6, and -7). In this paper, we… CONTINUE READING

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