Effectiveness of theophylline prophylaxis of renal impairment after coronary angiography in patients with chronic renal insufficiency.

@article{Huber2003EffectivenessOT,
  title={Effectiveness of theophylline prophylaxis of renal impairment after coronary angiography in patients with chronic renal insufficiency.},
  author={Wolfgang Huber and Chrysantha Schipek and Kathrin Ilgmann and M. J. T. Page and Michael Hennig and Annette Wacker and Ursula Schweigart and Leopoldo Lutilsky and Christian Valina and Melchior Seyfarth and Albert Schoemig and Meinhard Classen},
  journal={The American journal of cardiology},
  year={2003},
  volume={91 10},
  pages={
          1157-62
        }
}
Contrast media can lead to renal impairment that results in longer hospitalization and increased mortality. Adenosine is a crucial mediator of contrast-induced nephropathy (CIN; an increase in serum creatinine of >or=0.5 mg/dl within 48 hours). Therefore, it was the purpose of our study to investigate whether the adenosine antagonist theophylline reduces the incidence of CIN after coronary angiography. We also characterized risk factors for CIN after coronary angiography. One hundred patients… CONTINUE READING

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