Effectiveness of the pentavalent rotavirus vaccine in preventing gastroenteritis in the United States.

@article{Wang2010EffectivenessOT,
  title={Effectiveness of the pentavalent rotavirus vaccine in preventing gastroenteritis in the United States.},
  author={Florence T. Wang and Thomas Christopher Mast and Roberta J Glass and Jeanne Loughlin and John D. Seeger},
  journal={Pediatrics},
  year={2010},
  volume={125 2},
  pages={e208-13}
}
OBJECTIVE In clinical trials, the pentavalent rotavirus vaccine (RV5) was efficacious in preventing severe rotavirus gastroenteritis (RGE) and related health care encounters. We assessed the vaccine effectiveness (VE) of RV5 among US infants during the first 2 rotavirus seasons after vaccine licensure. METHODS Using a large, national, health insurance claim database, we monitored 2 cohorts of infants (infants who received 3 doses of RV5 and a concurrent group of infants who received 3 doses… CONTINUE READING

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