Effectiveness of sedation using nitrous oxide compared with enteral midazolam for botulinum toxin A injections in children.


This randomized, double-blind, placebo-controlled study compared the efficacy of inhaled nitrous oxide (N(2)O) with enteral midazolam for sedation of children with cerebral palsy (CP) undergoing botulinum toxin A (BoNT-A) injections. Fifty children (29 males, 21 females; mean age 8y 2mo [SD 4y 5mo]; range 1-16y) were randomized to sedation with N(2)O (n=25… (More)
DOI: 10.1111/j.1469-8749.2008.03069.x


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