Effectiveness of second-generation antipsychotics in patients with treatment-resistant schizophrenia: a review and meta-analysis of randomized trials.

@article{Chakos2001EffectivenessOS,
  title={Effectiveness of second-generation antipsychotics in patients with treatment-resistant schizophrenia: a review and meta-analysis of randomized trials.},
  author={Miranda Chakos and Jeffrey Lieberman and Eric Hoffman and Daniel Bradford and Brian B. Sheitman},
  journal={The American journal of psychiatry},
  year={2001},
  volume={158 4},
  pages={518-26}
}
OBJECTIVE The authors conducted a review and meta-analysis of studies that compared the efficacy and tolerability of typical and second-generation antipsychotics for patients with treatment-resistant schizophrenia. METHOD A systematic search revealed 12 controlled studies (involving 1,916 independent patients), which were included in the review. For the seven studies that compared clozapine to a typical antipsychotic, a meta-analysis was performed to examine clozapine's effects on overall… CONTINUE READING
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Meta-analytic procedures for social research

  • R. Rosenthal
  • 1986

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