Effectiveness of ramelteon for insomnia symptoms in older adults with obstructive sleep apnea: a randomized placebo-controlled pilot study.

@article{Gooneratne2010EffectivenessOR,
  title={Effectiveness of ramelteon for insomnia symptoms in older adults with obstructive sleep apnea: a randomized placebo-controlled pilot study.},
  author={Nalaka Gooneratne and Philip R Gehrman and Indira Gurubhagavatula and Erica Al-Shehabi and Elisabeth Mari{\'e} and Richard Schwab},
  journal={Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine},
  year={2010},
  volume={6 6},
  pages={
          572-80
        }
}
STUDY OBJECTIVES To evaluate the effectiveness of ramelteon, a melatonin receptor agonist, for the treatment of insomnia in older adults starting auto-titrating positive airway pressure (APAP) therapy for sleep apnea. METHODS A parallel group, randomized, double-blind, placebo-controlled pilot effectiveness clinical trial. The study enrolled 21 research study participants who were ≥ 60 years old and had obstructive sleep apnea, defined by an apnea-hypopnea index (AHI) ≥ 5 events/h, with… CONTINUE READING

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