Effectiveness of prophylactic use of rofecoxib in comparison with ibuprofen on postendodontic pain.

@article{Gopikrishna2003EffectivenessOP,
  title={Effectiveness of prophylactic use of rofecoxib in comparison with ibuprofen on postendodontic pain.},
  author={Velayutham Gopikrishna and Ananthnarayanan Parameswaran},
  journal={Journal of endodontics},
  year={2003},
  volume={29 1},
  pages={62-4}
}
The purpose of this study was to determine if prophylactic rofecoxib would significantly reduce postendodontic pain, when compared with ibuprofen or placebo. An additional objective was to establish if any relationship exists between periapical diagnosis and the need for additional medication after completion of pulpectomy. A total of 45 patients consented to a double-blind, single-dose oral administration of 50 mg of rofecoxib, 600 mg of ibuprofen, or a placebo before conventional root canal… CONTINUE READING