Effectiveness of oseltamivir in adults: a meta-analysis of published and unpublished clinical trials.

  title={Effectiveness of oseltamivir in adults: a meta-analysis of published and unpublished clinical trials.},
  author={Mark H. Ebell and Marlene Call and Joanna Shinholser},
  journal={Family practice},
  volume={30 2},
BACKGROUND Oseltamivir is widely used for the treatment of influenza. Previous systematic reviews suggest that they reduce complications, but had significant methodologic limitations. OBJECTIVE To assess the effect of oseltamivir on duration of symptoms, complications and hospitalizations in adults. METHODS We searched Medline without time or language restrictions, and trial registries maintained by the manufacturer. We included published and unpublished randomized double-blinded, placebo… CONTINUE READING
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