Effectiveness of olanzapine, quetiapine, and risperidone in patients with chronic schizophrenia after discontinuing perphenazine: a CATIE study.

@article{Stroup2007EffectivenessOO,
  title={Effectiveness of olanzapine, quetiapine, and risperidone in patients with chronic schizophrenia after discontinuing perphenazine: a CATIE study.},
  author={T. Scott Stroup and Jeffrey A. Lieberman and J P Mcevoy and Marvin S. Swartz and Sonia Marie Davis and George A Capuano and Robert A. Rosenheck and Richard S. E. Keefe and Alexander Luke Miller and Irving Belz and John K. Hsiao},
  journal={The American journal of psychiatry},
  year={2007},
  volume={164 3},
  pages={415-27}
}
OBJECTIVE The relative effectiveness of newly started antipsychotic drugs for individuals with schizophrenia may depend on multiple factors, including each patient's previous treatment response and the reason for a new medication trial. This randomized, double-blind study compared olanzapine, quetiapine, and risperidone in patients who had just discontinued the older antipsychotic perphenazine. METHOD Subjects with schizophrenia (N=114) who had been randomly assigned to and then discontinued… CONTINUE READING