Effectiveness of non-invasive ventilation in acute respiratory failure of obese patients: a brief narrative review

  title={Effectiveness of non-invasive ventilation in acute respiratory failure of obese patients: a brief narrative review},
  author={Maurizio A Cavalleri and Elena Barbagelata and Marco Scudeletti and Antonello Nicolini},
  journal={Italian Journal of Medicine},
Non-invasive ventilation (NIV) has been used successfully for the management of acute respiratory failure (ARF) more often in the last two decades compared to prior decades; nevertheless, NIV can have failure rates ranging from 5% to 50%. However, there are particular groups of patients that are more likely to benefit from NIV. One of these groups is patients with hypoventilation syndrome (OHS). The aim of this review is to seek evaluation of the effectiveness of NIV in acute setting. Only a… Expand
1 Citations
Non-Invasive Ventilation in Alveolar Obesity-Hypoventilation Syndrome
In this chapter, a brief review is made of what the most recent studies say regarding the treatment of SOHA with non-invasive ventilation (NIV), comparing different ventilation modes and/or treatments. Expand


Determinants of Noninvasive Ventilation Success or Failure in Morbidly Obese Patients in Acute Respiratory Failure
Multiple organ failure and pneumonia were the main factors associated with NIV failure and death in morbidly obese patients in hypoxemic ARF and NIV was constantly successful and could be safely pushed further in case of severe hypercapnic acute respiratory decompensation of OHS. Expand
Incidence and causes of non-invasive mechanical ventilation failure after initial success.
The occurrence of "late NIMV failure" was significantly associated with functional limitations (ADL scale) before admission to the respiratory ICU, the presence of medical complications (particularly hyperglycaemia), and a lower pH on admission. Expand
Noninvasive Ventilation for Acute Hypercapnic Respiratory Failure: Intubation Rate in an Experienced Unit
With a nurse-driven NIV protocol, the intubation rate was reduced to 15% in patients receiving NIV for AHRF, with a mortality rate of only 5%. Expand
The influence of severe obesity on non-invasive ventilation (NIV) strategies and responses in patients with acute hypercapnic respiratory failure attacks in the ICU.
It is suggested that improvement in hypercapnia in obese patients may require higher PEEP levels and longer times than that of non-obese patients during acute hypercapnic respiratory failure attack. Expand
Noninvasive ventilation for severely acidotic patients in respiratory intermediate care units
The objective of the present study was to compare NIV failure rates between patients with severe and non-severe acidosis admitted to a respiratory intermediate care unit (RICU) with AHRF resulting from ACPE, COPD or OHS. Expand
Survival of Hypercapnic Patients with COPD and Obesity Hypoventilation Syndrome Treated with High Intensity Non Invasive Ventilation in the Daily Routine Care
High intensity NIV within routine care is effective in reducing blood CO2 levels in COPD- and in OHS- related chronic respiratory insufficiency. Expand
Noninvasive ventilation in acute hypercapnic respiratory failure caused by obesity hypoventilation syndrome and chronic obstructive pulmonary disease.
Patients with OHS can be treated with NIV during an episode of AHRF with similar efficacy and better outcomes than patients with COPD, and obesity was associated with less late NIV failure and hospital readmission. Expand
Determinants of Noninvasive Ventilation Outcomes during an Episode of Acute Hypercapnic Respiratory Failure in Chronic Obstructive Pulmonary Disease: The Effects of Comorbidities and Causes of Respiratory Failure
The most important determinants of NIV outcome in COPD patients are the presence of pneumonia and the level of serum albumin as an indicator of the patient nutritional status. Expand
Noninvasive Ventilation in the Critically Ill Patient With Obesity Hypoventilation Syndrome: A Review
NIV of critically ill patients with acute respiratory failure and OHS; the indications for postoperative application of NIV in patients with OHS%; and the impact of OHS on weaning and postextubation respiratory failure are addressed. Expand
Associated factors with non-invasive mechanical ventilation failure in acute hypercapnic respiratory failure.
High APACHE II and C-reactive protein level, low Glasgow Coma Score, associated complication on admission and inadequate response in pH and PaCO(2) after first hour of NIMV are associated factors with NIMv failure. Expand