Effectiveness of mifamurtide in addition to standard chemotherapy for high-grade osteosarcoma: a systematic review

@article{Jimmy2017EffectivenessOM,
  title={Effectiveness of mifamurtide in addition to standard chemotherapy for high-grade osteosarcoma: a systematic review},
  author={R. Jimmy and Cindy Stern and K. Lisy and S. White},
  journal={JBI Database of Systematic Reviews and Implementation Reports},
  year={2017},
  volume={15},
  pages={2113–2152}
}
Background Osteosarcoma mostly occurs during the period of rapid bone growth in children and adolescents as high-grade osteosarcomas. Current treatment recommended for high-grade non-metastatic and metastatic and/or relapsed osteosarcoma involves neoadjuvant multiagent conventional chemotherapy, followed by surgical resection of macroscopically detected tumor and postoperative adjuvant chemotherapy. However, residual micrometastatic deposits that develop following surgery have shown resistance… Expand
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