Effectiveness of immunization with single and multi-component vaccines prepared from a common antigen (OEP), protease and elastase toxoids of Pseudomonas aeruginosa on protection against hemorrhagic pneumonia in mink due to P. aeruginosa.

@article{Homma1978EffectivenessOI,
  title={Effectiveness of immunization with single and multi-component vaccines prepared from a common antigen (OEP), protease and elastase toxoids of Pseudomonas aeruginosa on protection against hemorrhagic pneumonia in mink due to P. aeruginosa.},
  author={J Y Homma and Chiyoji Abe and Kenichi Tanamoto and Yoshihiko Hirao and Kazuyuki Morihara and Hiroshige Tsuzuki and Renpei Yanagawa and Eiichi Honda and Y Aoi and Yoshinori Fujimoto and Masanobu Goryo and Nobuo Imazeki and Hiromichi Noda and Artan Goda and Shotaro Takeuchi and Tomoaki Ishihara},
  journal={The Japanese journal of experimental medicine},
  year={1978},
  volume={48 2},
  pages={111-33}
}
Toxoids of protease and elastase of Pseudomonas aeruginosa were successfully prepared by treatment with 8% formalin plus 0.2 m lysine and by 4% formalin respectively. The two toxoids proved sufficiently potent to elicit high antibody titers as estimated by both the enzyme-neutralizing and passive hemagglutination tests. The effectiveness of immunizing minks with a single component-vaccine consisting of the common antigen (OEP) of P. aeruginosa or the protease toxoid (PT) or the elastase toxoid… CONTINUE READING