Effectiveness of early and aggressive administration of fresh frozen plasma to reduce massive blood transfusion during cytoreductive surgery.

@article{Saxena2013EffectivenessOE,
  title={Effectiveness of early and aggressive administration of fresh frozen plasma to reduce massive blood transfusion during cytoreductive surgery.},
  author={Akshat Saxena and Terence C Chua and Salwan Fransi and Winston Spencer Liauw and David L Morris},
  journal={Journal of gastrointestinal oncology},
  year={2013},
  volume={4 1},
  pages={30-9}
}
BACKGROUND Cytoreductive surgery (CRS) combined with perioperative intraperitoneal chemotherapy (PIC) has been consistently associated with high volume blood loss and red blood cell (RBC) transfusion. This study evaluates the effectiveness of the introduction of a novel protocol to reduce blood loss and subsequent intra-operative transfusion in patients with high volume disease. METHODS One hundred and thirty-one consecutive patients with high volume disease (peritoneal cancer index ≥16) who… CONTINUE READING

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