Effectiveness of atypical antipsychotic drugs in patients with Alzheimer's disease.

@article{Schneider2006EffectivenessOA,
  title={Effectiveness of atypical antipsychotic drugs in patients with Alzheimer's disease.},
  author={L. Schneider and P. Tariot and K. Dagerman and S. Davis and J. Hsiao and M. S. Ismail and B. Lebowitz and C. Lyketsos and J. M. Ryan and T. Stroup and D. Sultzer and D. Weintraub and J. Lieberman},
  journal={The New England journal of medicine},
  year={2006},
  volume={355 15},
  pages={
          1525-38
        }
}
  • L. Schneider, P. Tariot, +10 authors J. Lieberman
  • Published 2006
  • Medicine
  • The New England journal of medicine
  • BACKGROUND Second-generation (atypical) antipsychotic drugs are widely used to treat psychosis, aggression, and agitation in patients with Alzheimer's disease, but their benefits are uncertain and concerns about safety have emerged. We assessed the effectiveness of atypical antipsychotic drugs in outpatients with Alzheimer's disease. METHODS In this 42-site, double-blind, placebo-controlled trial, 421 outpatients with Alzheimer's disease and psychosis, aggression, or agitation were randomly… CONTINUE READING

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