Effectiveness of amantadine hydrochloride in the reduction of chronic traumatic brain injury irritability and aggression.

@article{Hammond2014EffectivenessOA,
  title={Effectiveness of amantadine hydrochloride in the reduction of chronic traumatic brain injury irritability and aggression.},
  author={Flora Hammond and Allison K Bickett and James H. Norton and Rashmi Pershad},
  journal={The Journal of head trauma rehabilitation},
  year={2014},
  volume={29 5},
  pages={
          391-9
        }
}
BACKGROUND Following traumatic brain injury (TBI), individuals may experience chronic problems with irritability or aggression, which may need treatment to minimize the negative impact on their relationships, home life, social interactions, community participation, and employment OBJECTIVE : To test the a priori hypothesis that amantadine reduces irritability (primary hypothesis) and aggression (secondary hypothesis) among individuals greater than 6 months post-TBI METHODS:: A total of 76… CONTINUE READING
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