Effectiveness of a trandolapril-based treatment regimen in subjects with isolated systolic hypertension in Canada.

@article{Tytus2009EffectivenessOA,
  title={Effectiveness of a trandolapril-based treatment regimen in subjects with isolated systolic hypertension in Canada.},
  author={Richard H Tytus and Ellen D Burgess and Linda Assouline and Anita Vanjaka},
  journal={Current medical research and opinion},
  year={2009},
  volume={25 6},
  pages={1379-84}
}
OBJECTIVE This report evaluates the effectiveness of a titration-based, escalating dose regimen based on trandolapril in subjects with isolated systolic hypertension (ISH) treated in Canadian clinical practice. METHODS Substudy of the TRAIL (Trandolapril Regimen Applied In real Life) study; a prospective, open-label, single cohort, multicentre study in 192 Canadian primary care practices. Subjects with ISH received trandolapril therapy, initiated at 1 mg/day (0.5 mg/day in subjects on… CONTINUE READING