Effectiveness of Light Therapy in Cognitively Impaired Persons: A Metaanalysis of Randomized Controlled Trials

  title={Effectiveness of Light Therapy in Cognitively Impaired Persons: A Metaanalysis of Randomized Controlled Trials},
  author={Huei-Ling Chiu and Pi-Tuan Chan and Hsin Chu and Shu-Tai Sheen Hsiao and Doresses Liu and Chueh-Ho Lin and Kuei-Ru Chou},
  journal={Journal of the American Geriatrics Society},
To explore the effects of light therapy on behavioral disturbances (BDs), sleep quality, and depression. 
10 Citations
The effects of bright light treatment on affective symptoms in people with dementia: a 24-week cluster randomized controlled trial
Compared to the control condition, affective symptoms were reduced after 16 weeks in the group receiving BLT, suggesting BLT may be beneficial for nursing home patients with dementia. Expand
Non-pharmacological interventions for sleep and quality of life: a randomized pilot study*
The effects found in this study provide information for sample size calculations and statistical power for confirmatory studies. Expand
Light interventions and sleep, circadian, behavioral, and psychological disturbances in dementia: A systematic review of methods and outcomes.
This systematic review provides a comprehensive overview of the effect of BLT in dementia, with a specific focus on how study characteristics might have affected the available results. Expand
A systematic review of non-pharmacological interventions to improve nighttime sleep among residents of long-term care settings
Although there was no clear pattern of positive findings, three interventions had the most promising results: increased daytime light exposure, nighttime use of melatonin, and acupressure. Expand
Pain, sleep disturbances and behavioural and psychological symptoms of dementia (BPSD) are common in nursing home (NH) patients with dementia. These symptoms are associated with and may trigger orExpand
Ambient bright light treatment improved proxy-rated sleep but not sleep measured by actigraphy in nursing home patients with dementia: a placebo-controlled randomised trial
Increasing daytime light exposure using bright light treatment (BLT) may represent a feasible non-pharmacological treatment for sleep problems in nursing home patients with dementia, according to the proxy-rated Sleep Disorder Inventory (SDI). Expand
Expert Consensus on the Care and Management of Patients with Cognitive Impairment in China
The cognitive disease consensus was prepared by panels of health and public representatives based on actual clinical practice in Geriatric Departments in Chinese hospitals and a systematic literatureExpand
Intervenciones no farmacológicas en el sueño y calidad de vida: estudio piloto aleatorizado
* Artículo parte de tesis de doctorado “Efetividade de intervenções não-farmacológicas no sono e qualidade de vida relacionada à saúde de pacientes com insuficiência cardíaca”, presentada en laExpand
  • Annette Sterr, James Ebajemito
  • Handbook of Sleep Disorders in Medical Conditions
  • 2019


Increasing Walking and Bright Light Exposure to Improve Sleep in Community‐Dwelling Persons with Alzheimer's Disease: Results of a Randomized, Controlled Trial
The effects of walking, light exposure, and a combination intervention (walking, light, and sleep education) on the sleep of persons with Alzheimer's disease (AD) are tested. Expand
Effect of timed bright light treatment for rest‐activity disruption in institutionalized patients with Alzheimer's disease
In most institutional environments, light levels are very low and may not be sufficient to entrain the circadian clock to the 24‐hour day. Expand
Effect of Bright Light Exposure on Depression and Agitation in Older Adults with Dementia
Findings support the use of bright light exposure to reduce depression and agitation in this population of persons with dementia residing in long-term care. Expand
Light therapy in the treatment of patients with bipolar depression: A meta-analytic study
A meta-analysis of nine studies examining the treatment effect of light therapy in bipolar depression found that disease severity was significantly decreased after LT, in both with and without TSD, and with concomitant medication. Expand
The effects of light therapy on sleep problems: A systematic review and meta-analysis.
To conclude, light therapy is effective for sleep problems in general, particularly for circadian outcomes and insomnia symptoms, however, most effect sizes are small to medium. Expand
Bright light therapy for agitation in dementia: a randomized controlled trial
There was limited evidence of reduction in agitation in people on active treatment, sleep was improved and a suggestion of greater efficacy in the winter months. Expand
Bright light therapy for nonseasonal depression: Meta-analysis of clinical trials.
BLT appears to be efficacious, particularly when administered for 2-5 weeks' duration and as monotherapy, and as Monotherapy. Expand
Light therapy for non-seasonal depression: systematic review and meta-analysis
Considering that light therapy has minimal side-effects and the authors' meta-analysis demonstrated that a significant proportion of patients achieved a clinically significant response, light therapy may be effective for patients with non-seasonal depression and can be a helpful additional therapeutic intervention for depression. Expand
The effect of exercise training on cognitive function in older adults with mild cognitive impairment: a meta-analysis of randomized controlled trials.
There is very limited evidence that exercise improves cognitive function in individuals with MCI, although published research is of moderate quality and inconclusive due to low statistical power. Expand
Effect of home-based light treatment on persons with dementia and their caregivers
Six weeks of modest doses of blue-white light appear to improve sleep in caregivers but not in people with dementia, and greater or prolonged circadian stimulation may be needed to determine if light is an effective treatment for persons with dementia. Expand