Effectiveness of Light Therapy in Cognitively Impaired Persons: A Metaanalysis of Randomized Controlled Trials

  title={Effectiveness of Light Therapy in Cognitively Impaired Persons: A Metaanalysis of Randomized Controlled Trials},
  author={Huei-Ling Chiu and Pi-Tuan Chan and Hsin Chu and Shu-Tai Sheen Hsiao and Doresses Liu and Chueh-Ho Lin and Kuei-Ru Chou},
  journal={Journal of the American Geriatrics Society},
To explore the effects of light therapy on behavioral disturbances (BDs), sleep quality, and depression. 
15 Citations
The effects of bright light treatment on affective symptoms in people with dementia: a 24-week cluster randomized controlled trial
Compared to the control condition, affective symptoms were reduced after 16 weeks in the group receiving BLT, suggesting BLT may be beneficial for nursing home patients with dementia.
Pilot Study of the Effects of Bright Ambient Therapy on Dementia Symptoms and Cognitive Function
A 4-week regimen of bright light therapy was the most effective, with higher adherence and acceptability, and differences in outcomes between the 5th and 9th weeks were not significant.
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The effects found in this study provide information for sample size calculations and statistical power for confirmatory studies.
Light, sleep‐wake rhythm, and behavioural and psychological symptoms of dementia in care home patients: Revisiting the sundowning syndrome
Conceptual models of sundowning phenomena have shifted emphasis from the role of light in vision in vision to its role in circadian rhythm modulation, but the grounds for this change are unclear and the evidence on which it is based has not been examined comprehensively.
A systematic review of non-pharmacological interventions to improve nighttime sleep among residents of long-term care settings
Although there was no clear pattern of positive findings, three interventions had the most promising results: increased daytime light exposure, nighttime use of melatonin, and acupressure.
Non-Pharmacological Treatments of Neuropsychiatric Symptoms in Mild Cognitive Impairment (MCI).
The limited number of studies specific to individuals with MCI and its various etiologies, as well as the overall heterogeneity of research design and methodologies, make the evidence base inconclusive, Nevertheless, some studies support psychosocial interventions aimed at individuals withMCI and their caregivers.
Pain, sleep disturbances and behavioural and psychological symptoms of dementia (BPSD) are common in nursing home (NH) patients with dementia. These symptoms are associated with and may trigger or
Expert Consensus on the Care and Management of Patients with Cognitive Impairment in China
The cognitive disease consensus was prepared by panels of health and public representatives based on actual clinical practice in Geriatric Departments in Chinese hospitals and a systematic literature
Intervenciones no farmacológicas en el sueño y calidad de vida: estudio piloto aleatorizado
* Artículo parte de tesis de doctorado “Efetividade de intervenções não-farmacológicas no sono e qualidade de vida relacionada à saúde de pacientes com insuficiência cardíaca”, presentada en la


Effect of timed bright light treatment for rest‐activity disruption in institutionalized patients with Alzheimer's disease
In most institutional environments, light levels are very low and may not be sufficient to entrain the circadian clock to the 24‐hour day.
Effect of Bright Light Exposure on Depression and Agitation in Older Adults with Dementia
Findings support the use of bright light exposure to reduce depression and agitation in this population of persons with dementia residing in long-term care.
Bright light therapy for agitation in dementia: a randomized controlled trial
There was limited evidence of reduction in agitation in people on active treatment, sleep was improved and a suggestion of greater efficacy in the winter months.
Bright light therapy for nonseasonal depression: Meta-analysis of clinical trials.
Light therapy for non-seasonal depression: systematic review and meta-analysis
Considering that light therapy has minimal side-effects and the authors' meta-analysis demonstrated that a significant proportion of patients achieved a clinically significant response, light therapy may be effective for patients with non-seasonal depression and can be a helpful additional therapeutic intervention for depression.
The effect of exercise training on cognitive function in older adults with mild cognitive impairment: a meta-analysis of randomized controlled trials.
Effect of home-based light treatment on persons with dementia and their caregivers
Six weeks of modest doses of blue-white light appear to improve sleep in caregivers but not in people with dementia, and greater or prolonged circadian stimulation may be needed to determine if light is an effective treatment for persons with dementia.
Sleep, Cognitive impairment, and Alzheimer’s disease: A Systematic Review and Meta-Analysis
A broad systematic review and meta-analysis confirmed the association between sleep and cognitive impairment or AD and consolidated the evidence to provide an "average" magnitude of effect.
Light therapy for improving cognition, activities of daily living, sleep, challenging behaviour, and psychiatric disturbances in dementia.
This updated review found no effect of light therapy on cognitive function, sleep, challenging behaviour (for example agitation), or psychiatric symptoms associated with dementia.