Effectiveness of Ivabradine Treatment in Different Subpopulations with Stable Angina in Clinical Practice: A Pooled Analysis of Observational Studies.

@article{Werdan2016EffectivenessOI,
  title={Effectiveness of Ivabradine Treatment in Different Subpopulations with Stable Angina in Clinical Practice: A Pooled Analysis of Observational Studies.},
  author={Karl Werdan and Stefan Perings and Ralf K{\"o}ster and Malte Kelm and Thomas Meinertz and Georg Stoeckl and Ursula Mueller-Werdan},
  journal={Cardiology},
  year={2016},
  volume={135 3},
  pages={141-150}
}
OBJECTIVES The efficacy of ivabradine has been demonstrated in different subpopulations of stable angina patients in randomized clinical trials. This study explored its effectiveness in subpopulations seen in clinical practice as they often differ from those of randomized trials. METHODS Data were pooled from three German observational studies with similar inclusion criteria (stable angina and heart rate ≥60 bpm). All patients received 2.5, 5, or 7.5 mg b.i.d. of ivabradine for 4 months, with… CONTINUE READING

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