Effectiveness of Intravenous Infusion Algorithms for Glucose Control in Diabetic Patients Using Different Simulation Models.

@article{Farmer2009EffectivenessOI,
  title={Effectiveness of Intravenous Infusion Algorithms for Glucose Control in Diabetic Patients Using Different Simulation Models.},
  author={Terry G Farmer and Thomas F. Edgar and Nicholas A Peppas},
  journal={Industrial & engineering chemistry research},
  year={2009},
  volume={48 9},
  pages={4402-4414}
}
The effectiveness of closed-loop insulin infusion algorithms is assessed for three different mathematical models describing insulin and glucose dynamics within a Type I diabetes patient. Simulations are performed to assess the effectiveness of proportional plus integral plus derivative (PID) control, feedforward control, and a physiologically-based control system with respect to maintaining normal glucose levels during a meal and during exercise. Control effectiveness is assessed by comparing… CONTINUE READING