Effectiveness of Chlorthalidone Plus Amiloride for the Prevention of Hypertension: The PREVER‐Prevention Randomized Clinical Trial

Abstract

BACKGROUND Prehypertension is associated with higher cardiovascular risk, target organ damage, and incidence of hypertension. The Prevention of Hypertension in Patients with PreHypertension (PREVER-Prevention) trial aimed to evaluate the efficacy and safety of a low-dose diuretic for the prevention of hypertension and end-organ damage. METHODS AND RESULTS… (More)

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@inproceedings{Fuchs2016EffectivenessOC, title={Effectiveness of Chlorthalidone Plus Amiloride for the Prevention of Hypertension: The PREVER‐Prevention Randomized Clinical Trial}, author={Sandra Costa Fuchs and Carlos E. Poli‐de‐Figueiredo and Jos{\'e} Albuquerque de Figueiredo Neto and Luiz C{\'e}sar Naz{\'a}rio Scala and Paul Kieran Whelton and Francisca Mosele and Renato Gorga Bandeira de Mello and Jos{\'e} F. Vilela‐Martin and Leila Beltrami Moreira and Hilton Chaves and Marco Mota Gomes and Marcos Roberto de Sousa and Ricardo Pereira e Silva and I. N{\'u}{\~n}ez de Castro and Evandro Jos{\'e} Cesarino and Paulo C{\'e}sar Brand{\~a}o Veiga Jardim and Jo{\~a}o Alves and Andr{\'e} Avelino Steffens and Andr{\'e}a Ara{\'u}jo Brand{\~a}o and Fernanda M. Consolim‐Colombo and Paulo Ricardo de Alencastro and Abrah{\~a}o Afiune Neto and A. C. L. da Nobrega and Roberto Yuri da Silva Franco and D{\'a}rio Celestino Sobral Filho and Alexandro Bordignon and Fernando Nobre and Rosane Paix{\~a}o Schlatter and Miguel Gus and Felipe Costa Fuchs and Ot{\'a}vio Berwanger and Fl{\'a}vio Danni Fuchs}, booktitle={Journal of the American Heart Association}, year={2016} }