Effectiveness and toxicity screening of various absorption enhancers in the large intestine: intestinal absorption of phenol red and protein and phospholipid release from the intestinal membrane.

@article{Uchiyama1996EffectivenessAT,
  title={Effectiveness and toxicity screening of various absorption enhancers in the large intestine: intestinal absorption of phenol red and protein and phospholipid release from the intestinal membrane.},
  author={Tomomi Uchiyama and Akira Yamamoto and Hiroshi Hatano and Takuya Fujita and Shozo Kansantachibana-cho Muranishi},
  journal={Biological & pharmaceutical bulletin},
  year={1996},
  volume={19 12},
  pages={
          1618-21
        }
}
The effectiveness and local toxicity of absorption enhancers on the absorption of phenol red (PR) from the large intestine of rats were examined using an in situ loop method. The absorption enhancers used in this study were sodium glycocholate (GC-Na), sodium taurocholate (TC-Na), sodium deoxycholate (DC-Na), EDTA, sodium salicylate (Sal-Na), sodium caprate (Cap-Na), diethyl maleate (DM), N-lauryl-beta-D-maltopyranoside (LM) and mixed micelles (MM), all used at a concentration of 20 mM. Local… CONTINUE READING
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