Effectiveness and safety of liposomal amphotericin B for visceral leishmaniasis under routine program conditions in Bihar, India.

@article{Sinha2010EffectivenessAS,
  title={Effectiveness and safety of liposomal amphotericin B for visceral leishmaniasis under routine program conditions in Bihar, India.},
  author={Prabhat Kumar Sinha and Paul Roddy and Pedro Pablo Palma and Alice Kociejowski and Mar{\'i}a Angeles Lima and Vidya Nand Rabi Das and Jitendra Gupta and Nawin Kumar and Gaurab Mitra and Jean-François Saint-Sauveur and Siju Seena and Manica Balasegaram and Fernando Parre{\~n}o and Krishna Pandey},
  journal={The American journal of tropical medicine and hygiene},
  year={2010},
  volume={83 2},
  pages={357-64}
}
We evaluated, through the prospective monitoring of 251 patients at Sadar Hospital in Bihar, India, the effectiveness and safety of 20 mg/kg body weight of liposomal amphotericin B for the treatment of visceral leishmaniasis. The treatment success rates for the intention-to-treat, per protocol, and intention-to-treat worse-case scenario analyses were 98.8%, 99.6%, and 81.3%, respectively. Nearly one-half of patients experienced mild adverse events, but only 1% developed serious but non-life… CONTINUE READING
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Communicable Diseases , Kala - Azar status in SEA Region

  • P Desjeux
  • 2009

AmBisome ( Amphotericin B ) Liposome for Injection

  • C Schmid, S Nkunku, A Merolle, P Vounatsou, C Burri
  • 2007

Effectiveness of a 10 - day melarsoprol schedule for the treatment of late - stage human African trypanosomiasis : confirmation from a multinational study ( impamel II )

  • F Checchi, P Piola, H Ayikoru, F Thomas, D Legros, G Priotto
  • J Infect Dis
  • 2005

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