Effective treatment of traumatic brain injury: learning from experience.

  title={Effective treatment of traumatic brain injury: learning from experience.},
  author={Robert Louis Ruff and Ronald George Riechers},
  volume={308 19},
IN THIS ISSUE OF JAMA, ZAFONTE AND COLLEAGUES 1 PREsent the findings of the Citicoline Brain Injury Treatment Trial (COBRIT), a phase 3, double-blind study comparing citicoline vs placebo. In this trial, 1213 study participants with complicated mild, moderate, or severe traumatic brain injury (TBI) were randomized to receive 2000 mg of citicoline or placebo daily for 90 days. The study, which did not demonstrate any benefits of citicholine treatment, is likely to have implications not only for… CONTINUE READING
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A case-control study examining whether neurological deficits and PTSD in combat veterans are related to episodes of mild TBI

  • RL Ruff, RG IIRiechers, X-F Wang, T Piero, SS. Ruff
  • BMJ Open
  • 2012

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