Effective treatment of advanced biliary tract carcinoma using 5-fluorouracil continuous infusion with cisplatin.

@article{Ducreux1998EffectiveTO,
  title={Effective treatment of advanced biliary tract carcinoma using 5-fluorouracil continuous infusion with cisplatin.},
  author={Michel P Ducreux and Philippe Rougier and Abderrahim Fandi and M-C Clavero-Fabri and Andr Villing and Flavia Fassone and L Fandi and Juan Jos{\'e} Zarb{\'a} and Jean Pierre Armand},
  journal={Annals of oncology : official journal of the European Society for Medical Oncology},
  year={1998},
  volume={9 6},
  pages={653-6}
}
BACKGROUND The combination of 5-fluorouracil (5-FU) and cisplatin has shown great activity in many different types of tumour with an in vitro synergistic effect between 5-FU and cisplatin. A phase II study of 5-FU plus cisplatin was performed in 25 previously untreated patients with inoperable locally advanced or metastatic biliary tract carcinoma. PATIENTS AND METHODS Twenty-five patients, 10 of them men and 15 women with a median age of 58, were entered into the study. The chemotherapy… CONTINUE READING
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