Effective ribozyme delivery in plant cells ( tRNA / hammerhead )

@inproceedings{Bruening2005EffectiveRD,
  title={Effective ribozyme delivery in plant cells ( tRNA / hammerhead )},
  author={George E Bruening and E. S. DENNISt and W. J. PEACOCKt},
  year={2005}
}
Hammerhead ribozyme sequences were incorporated into a tyrosine tRNA (tRNATYr) and compared with nonembedded molecules. To increase the levels of ribozyme and control antisense in vivo, sequences were expressed from an autonomously replicating vector derived from African cassava mosaic geminivirus. In vitro, the nonembedded ribozyme cleaved more target RNA… CONTINUE READING