Effective prostate cancer chemopreventive intervention with green tea polyphenols in the TRAMP model depends on the stage of the disease.

@article{Adhami2009EffectivePC,
  title={Effective prostate cancer chemopreventive intervention with green tea polyphenols in the TRAMP model depends on the stage of the disease.},
  author={Vaqar Mustafa Adhami and Imtiaz Ahmad Siddiqui and Sami Sarfaraz and Sabih Islam Khwaja and Bilal Bin Hafeez and Noor Hidayah Tauhid Ahmad and Hasan Mukhtar},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={2009},
  volume={15 6},
  pages={
          1947-53
        }
}
PURPOSE We have shown previously that oral feeding of green tea polyphenols (GTP) to transgenic adenocarcinoma of the mouse prostate mice in a purely chemopreventive setting significantly inhibits prostate cancer development. To translate this to a human situation, the present study was designed to identify the stage of prostate cancer that is most vulnerable to chemopreventive intervention by GTP. EXPERIMENTAL DESIGN GTP infusion (0.1% in drinking water) to transgenic adenocarcinoma of the… CONTINUE READING

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