Effective prophylactic therapy for cyclic vomiting syndrome in children using valproate.


This trial sought to evaluate our experience using the antimigraine prophylactic drug, use of valproate for the prophylactic management of cyclic vomiting syndrome (CVS) in children. Thirteen children diagnosed with severe CVS were enrolled. Prophylactic therapy consisted of valproate administered at a dose of 10-40 mg/kg/day. Upon enrollment in the study… (More)
DOI: 10.1016/j.braindev.2008.07.005


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