• DOI:10.1038/nrg2526
Corpus ID: 205484393

Effective population size and patterns of molecular evolution and variation

@article{Charlesworth2009EffectivePS,
  title={Effective population size and patterns of molecular evolution and variation},
  author={B. Charlesworth},
  journal={Nature Reviews Genetics},
  year={2009},
  volume={10},
  pages={195-205}
}

B. Charlesworth

Published 2009

Biology, Medicine

Nature Reviews Genetics

The effective size of a population, Ne, determines the rate of change in the composition of a population caused by genetic drift, which is the random sampling of genetic variants in a finite population. Ne is crucial in determining the level of variability in a population, and the effectiveness of selection relative to drift. This article reviews the properties of Ne in a variety of different situations of biological interest, and the factors that influence it. In particular, the action of… CONTINUE READING

View on Nature

people.bu.edu

Save to Library

Create Alert

Cite

Launch Research Feed