Effective population size and patterns of molecular evolution and variation

@article{Charlesworth2009EffectivePS,
  title={Effective population size and patterns of molecular evolution and variation},
  author={Brian Charlesworth},
  journal={Nature Reviews Genetics},
  year={2009},
  volume={10},
  pages={195-205}
}

• Brian Charlesworth
• Published 2009 in Nature Reviews Genetics
• DOI:10.1038/nrg2526

The effective size of a population, Ne, determines the rate of change in the composition of a population caused by genetic drift, which is the random sampling of genetic variants in a finite population. Ne is crucial in determining the level of variability in a population, and the effectiveness of selection relative to drift. This article reviews the properties of Ne in a variety of different situations of biological interest, and the factors that influence it. In particular, the action of… CONTINUE READING

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