Effective population size and patterns of molecular evolution and variation
@article{Charlesworth2009EffectivePS, title={Effective population size and patterns of molecular evolution and variation}, author={B. Charlesworth}, journal={Nature Reviews Genetics}, year={2009}, volume={10}, pages={195-205} }
The effective size of a population, Ne, determines the rate of change in the composition of a population caused by genetic drift, which is the random sampling of genetic variants in a finite population. Ne is crucial in determining the level of variability in a population, and the effectiveness of selection relative to drift. This article reviews the properties of Ne in a variety of different situations of biological interest, and the factors that influence it. In particular, the action of… CONTINUE READING
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