Effective inhibition of cancer cell growth by a novel tripartite transfection complex containing ribbon antisense molecules to hTR.

  • Jong-gu Park
  • Published 2004 in
    Cancer research and treatment : official journal…

Abstract

PURPOSE In the present study, ribbon antisense to the hTR RNA, a component of the telomerase complex, was employed to inhibit telomerase activity and cancer cell growth. MATERIALS AND METHODS Ribbon antisense molecules to the human hTR gene (hTR-RiAS) were constructed and complexed with a short modified peptide and cationic liposomes to improve the… (More)
DOI: 10.4143/crt.2004.36.5.308

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