Effective inhaled drug administration to mechanically ventilated patients.

  title={Effective inhaled drug administration to mechanically ventilated patients.},
  author={Rajiv Dhand and Emmanuelle Mercier},
  journal={Expert opinion on drug delivery},
  volume={4 1},
Inhaled therapy is commonly employed in mechanically ventilated patients with chronic obstructive pulmonary disease or asthma. The efficacy of inhaled drugs is comparable to that achieved with systemic routes of administration, but the dose of drug required to achieve a therapeutic effect is generally much smaller. Moreover, limited systemic absorption of inhaled drugs minimises systemic side effects. Aerosol administration to ventilated patients differs from that in ambulatory patients in… CONTINUE READING