Effective induction of apoptosis in human prostate carcinoma cells by vitamin E succinate


Cytotoxicity of VES against the cell lines LNCaP, DU145 and PC5 was measured in continuously rising concentrations from 10 to 100mg=ml VES by a MTT assay. The VES concentrations which resulted in a 50% cell death rate (IC50 values) were evaluated. In the cell line LNCaP, the relative amount of apoptotic cells after a 24 h incubation in increasing VES… (More)
DOI: 10.1038/sj.pcan.4500356