Effective generation of iPS cells from CD34+ cord blood cells by inhibition of p53.

@article{Takenaka2010EffectiveGO,
  title={Effective generation of iPS cells from CD34+ cord blood cells by inhibition of p53.},
  author={Chiemi Takenaka and Naoki Nishishita and Nozomi Takada and Lars Martin Jakt and Shin Kawamata},
  journal={Experimental hematology},
  year={2010},
  volume={38 2},
  pages={154-62}
}
OBJECTIVE Cord blood banks provide fully human leukocyte antigen-typed cells, from which a set of standard induced pluripotent stem (iPS) cells for use in allogenic transplantation can be derived. Hence, the ability to generate iPS cells from cord blood cells has the potential to provide a suitable source for clinical transplantation. The aim of this work is to determine the reprogramming methods, culture conditions, and cell fractions that can be used to generate iPS cells from cord blood… CONTINUE READING
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