Effective control of refractory pulmonary hypertension after cardiac operations.

  title={Effective control of refractory pulmonary hypertension after cardiac operations.},
  author={David Fullerton and James J Jaggers and Fran Piedalue and Frederick L. Grover and Robert C. McIntyre},
  journal={The Journal of thoracic and cardiovascular surgery},
  volume={113 2},
  pages={363-8; discussion 368-70}
OBJECTIVES Inhaled nitric oxide is a promising therapy to control pulmonary hypertension. However, pulmonary hypertension caused by valvular heart disease is often refractory to inhaled nitric oxide. The objective of this study was to determine whether the combination of inhaled nitric oxide plus dipyridamole will cause a response in patients with pulmonary hypertension undergoing cardiac operations who had not responded to inhaled nitric oxide alone. METHODS Responses in 10 patients (62… CONTINUE READING


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